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Ainhum (from the Yoruba word ayùn meaning "to saw" or "fissure") — also known as dactylolysis spontanea — is a rare, progressive constricting fibrous band disorder that develops around the base of a digit, most commonly the fifth toe, leading eventually to autoamputation.

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It is a noninfectious, idiopathic constrictive phenomenon that affects dark-skinned adults in tropical regions (Africa, India, South America).

![The word "ainhum" comes from an African word that means "to saw or cut". True ainhum, also known as dactylolysis spontanea, is a disorder that affects soft tissue or digits with constricting rings and typically manifests in the fifth toe. We describe a rare instance of genuine ainhum that only affected the left fifth toe. Few cases have ever been reported globally, and this one is extremely rare. South Africa and South America have been found to have the highest incidence of ainhum. In India, it is seldom ever recorded. Ainhum when diagnosed and treated in the early stages can be prevented from progressing to mutilating deformities. In the case presented here, a 60-year-old woman complained of pain and swelling on her left fifth toe, which was free of any ulceration or discharge. The patient described a minor injury to the left fifth toe two months prior to seeking our help, which was followed by altered sensation before the situation eventually worsened to what it is now, with no signs of gangrene or other skin abnormalities. Every peripheral pulse was felt. He lacked any localized lymphadenopathy. Upon closer inspection, it was discovered that the left fifth toe´s proximal interphalangeal joint level had a band-like soft tissue constriction. An X-ray of the left foot revealed a constricting band that was so deep that it separated the distal segment almost to the point of auto-amputation in the middle of the proximal phalanx.

Madasu Sai Vikas et al. A case of “ainhum”: a rare clinical image. Pan African Medical Journal. 2023;44:129. [doi: 10.11604/pamj.2023.44.129.39066]](attachment:6ff88d47-8024-4ddb-99fa-8b6155b7ecd4:fig1.png)

The word "ainhum" comes from an African word that means "to saw or cut". True ainhum, also known as dactylolysis spontanea, is a disorder that affects soft tissue or digits with constricting rings and typically manifests in the fifth toe. We describe a rare instance of genuine ainhum that only affected the left fifth toe. Few cases have ever been reported globally, and this one is extremely rare. South Africa and South America have been found to have the highest incidence of ainhum. In India, it is seldom ever recorded. Ainhum when diagnosed and treated in the early stages can be prevented from progressing to mutilating deformities. In the case presented here, a 60-year-old woman complained of pain and swelling on her left fifth toe, which was free of any ulceration or discharge. The patient described a minor injury to the left fifth toe two months prior to seeking our help, which was followed by altered sensation before the situation eventually worsened to what it is now, with no signs of gangrene or other skin abnormalities. Every peripheral pulse was felt. He lacked any localized lymphadenopathy. Upon closer inspection, it was discovered that the left fifth toe´s proximal interphalangeal joint level had a band-like soft tissue constriction. An X-ray of the left foot revealed a constricting band that was so deep that it separated the distal segment almost to the point of auto-amputation in the middle of the proximal phalanx.

Madasu Sai Vikas et al. A case of “ainhum”: a rare clinical image. Pan African Medical Journal. 2023;44:129. [doi: 10.11604/pamj.2023.44.129.39066]

Epidemiology


Parameter Details
Incidence Rare; higher in West Africa, South India, Brazil
Age group Adults aged 20–50 years
Sex Male predominance (2–3:1)
Digit involved Fifth toe (≈75% cases), less commonly fourth or other toes
Laterality Often bilateral (~25–50%)
Ethnic predilection More common in African and Dravidian populations

Etiopathogenesis


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Progressive fibrous band formation around the toe → vascular and lymphatic compromisedistal bone resorption and atrophyautoamputation.

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The exact cause remains unknown, but several hypotheses exist:

Proposed Mechanism Description
Chronic trauma / friction Walking barefoot in tropical climates causes recurrent minor trauma → fibrosis at digital base.
Vascular compromise Endarteritis or arteriolar spasm → ischemic fibrosis.
Infection or inflammation Local infection may trigger abnormal fibrotic response.
Genetic predisposition Familial clustering noted.
Idiopathic fibrosis Spontaneous constrictive scarring in predisposed individuals.

Clinical Features


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Characteristic appearance:Constricting groove at the base of the fifth toe” with distal bulbous swelling.

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Symptoms:

Stage Findings
Stage I (Early) Development of a shallow groove or constricting band at the base of the fifth toe; often painless.
Stage II Band deepens → swelling and distal bulbous enlargement due to lymphatic obstruction; intermittent pain.
Stage III Band tightens → bone resorption and joint destruction → increased pain, ulceration, secondary infection.
Stage IV (Late) Complete separation (autoamputation) of the distal phalanx; usually painless at separation.

Sites of Involvement