![Claw sign. Wilms tumor in a 2-year-old boy with typical claw sign (arrows). Contrast-enhanced T1-w MRI in axial (a) and coronal (b) orientation. The claw sign can be seen here, derives from the sharp angles on both sides of the tumor formed by the surrounding normal organ parenchyma. These angles can only be detected if the tumor originates from the organ itself and displaces or thins out the parenchyma. Typically, it can help for the differentiation of a Wilms tumor from a neuroblastoma
Pathognomonic imaging signs in abdominal radiology - Scientific Figure on ResearchGate. Available from: https://www.researchgate.net/figure/Claw-sign-Wilms-tumor-in-a-2-year-old-boy-with-typical-claw-sign-arrows_fig16_337931968 [accessed 25 Aug, 2022]](https://s3-us-west-2.amazonaws.com/secure.notion-static.com/a75937eb-41c8-45f5-8b0c-4babd58167c1/Untitled.png)
Claw sign. Wilms tumor in a 2-year-old boy with typical claw sign (arrows). Contrast-enhanced T1-w MRI in axial (a) and coronal (b) orientation. The claw sign can be seen here, derives from the sharp angles on both sides of the tumor formed by the surrounding normal organ parenchyma. These angles can only be detected if the tumor originates from the organ itself and displaces or thins out the parenchyma. Typically, it can help for the differentiation of a Wilms tumor from a neuroblastoma
Pathognomonic imaging signs in abdominal radiology - Scientific Figure on ResearchGate. Available from: https://www.researchgate.net/figure/Claw-sign-Wilms-tumor-in-a-2-year-old-boy-with-typical-claw-sign-arrows_fig16_337931968 [accessed 25 Aug, 2022]

Solid pseudopapillary epithelial neoplasm of the pancreas in a 28-year-old female. IV contrast-enhanced axial CT demonstrates a well-defined, heterogeneous mass anterior to the body and tail of the pancreas. Presence of the claw sign (arrows) suggests this mass to be arising from the pancreatic parenchyma.
Scali, E.P., Chandler, T.M., Heffernan, E.J. et al. Primary retroperitoneal masses: what is the differential diagnosis?. Abdom Imaging 40, 1887–1903 (2015). https://doi.org/10.1007/s00261-014-0311-x

Dedifferentiated retroperitoneal liposarcoma in an 84-year-old female. IV- and oral-contrast enhanced sagittal CT reformat illustrates an absent claw sign (arrows) between the mass and the kidney, which excludes a renal origin in this case.
Scali, E.P., Chandler, T.M., Heffernan, E.J. et al. Primary retroperitoneal masses: what is the differential diagnosis?. Abdom Imaging 40, 1887–1903 (2015). https://doi.org/10.1007/s00261-014-0311-x