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A fibroadenoma is a benign, hormonally responsive, fibroepithelial tumor of the breast, most commonly seen in young women aged 15–35 years. It consists of both stromal and epithelial elements and represents the most common palpable breast mass in women under 30.

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https://www.youtube.com/watch?v=jh-8fun2S8U

Pathology

• Arises from the Terminal duct-lobular unit (TDLU)
• Composed of:
  • Proliferating stroma
  • Compressed or distorted epithelial ducts
• Two histological patterns:
  1. Pericanalicular – stroma surrounds patent ducts
  2. Intracanalicular – stroma compresses ducts into slit-like spaces

Variants:

Clinical Features

• Firm, rubbery, mobile, well-circumscribed breast mass
• Typically painless and slowly enlarging
• Size may increase during pregnancy or hormonal therapy
• Usually solitary, but may be multiple or bilateral

Radiology

![MG images of three different patients; involutional, benign calcifications are detected. In a 53-year-old female patient, the occurrence and proliferation of benign popcorn calcifications from peripheral to central zone between 2003 and 2018 are seen (a). In a 57-year-old female patient, there are dystrophic calcifications occurred at early stage of involution (arrow) (b).

Akin IB, Pinar Balci. Fibroadenomas: a multidisciplinary review of the variants. Clinical Imaging. 2020;71:83-100. doi:https://doi.org/10.1016/j.clinimag.2020.10.058](attachment:c980f74e-0e6d-4ae6-bb2d-ad2a2eadea85:1-s2.0-S0899707120304228-gr2_lrg.jpg)

MG images of three different patients; involutional, benign calcifications are detected. In a 53-year-old female patient, the occurrence and proliferation of benign popcorn calcifications from peripheral to central zone between 2003 and 2018 are seen (a). In a 57-year-old female patient, there are dystrophic calcifications occurred at early stage of involution (arrow) (b).

Akin IB, Pinar Balci. Fibroadenomas: a multidisciplinary review of the variants. Clinical Imaging. 2020;71:83-100. doi:https://doi.org/10.1016/j.clinimag.2020.10.058

![B mod US image of 32-year-old female patient; there is oval shaped, well circumscribed, hypoechoic solid lesion. The lesion is in parallel orientation to breast tissue and skin (a). US images of two different SFAs; there are echogenic fibrous septa (arrows) (b). A-36-year-old female patient, ovoid, well defined, SFA diagnosed lesion, US image reveals an echogenic perilesional pdeudocapsular structure formed due to peripheral breast parenchymal compression (arrows) (c). Heterogeneous, irregular shaped, vertical orientated solid lesion. There is a posterior acoustic shadowing. In MG examination there are calcifications in this SFA diagnosed lesion (d). US images of a cyst (e) and SFA (f); there are posterior acoustic enhancements (arrows). The enhancement is cleaner in cyst.

Akin IB, Pinar Balci. Fibroadenomas: a multidisciplinary review of the variants. Clinical Imaging. 2020;71:83-100. doi:https://doi.org/10.1016/j.clinimag.2020.10.058](attachment:889b9540-3a80-46bc-8dda-78c50d5aadab:1-s2.0-S0899707120304228-gr3_lrg.jpg)

B mod US image of 32-year-old female patient; there is oval shaped, well circumscribed, hypoechoic solid lesion. The lesion is in parallel orientation to breast tissue and skin (a). US images of two different SFAs; there are echogenic fibrous septa (arrows) (b). A-36-year-old female patient, ovoid, well defined, SFA diagnosed lesion, US image reveals an echogenic perilesional pdeudocapsular structure formed due to peripheral breast parenchymal compression (arrows) (c). Heterogeneous, irregular shaped, vertical orientated solid lesion. There is a posterior acoustic shadowing. In MG examination there are calcifications in this SFA diagnosed lesion (d). US images of a cyst (e) and SFA (f); there are posterior acoustic enhancements (arrows). The enhancement is cleaner in cyst.

Akin IB, Pinar Balci. Fibroadenomas: a multidisciplinary review of the variants. Clinical Imaging. 2020;71:83-100. doi:https://doi.org/10.1016/j.clinimag.2020.10.058