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Osgood–Schlatter disease (OSD) is a self-limiting traction apophysitis of the tibial tuberosity, occurring due to repetitive stress from the patellar tendon on a developing ossification center.

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Osgood-Schlatter disease - causes, symptoms, diagnosis, treatment, pathology

https://youtu.be/AZt21fpR6qQ

https://youtu.be/cWmgdE9boUs

https://youtu.be/yQfbwzaUuKo

Pathophysiology


Feature Description
Mechanism Repetitive strain on the immature secondary ossification center of the tibial tubercle
Growth period Occurs during adolescence (age 10–15)
Gender predilection More common in males (but increasing in active females)
Laterality Bilateral in 20–30% of cases

Clinical Features


Feature Description
Symptoms Anterior knee pain, worsened by activity (jumping, squatting)
Pain location Over tibial tuberosity, tender to palpation
Swelling Localized, firm bump may be present
Onset Gradual; associated with periods of increased activity
Range of motion Normal or slightly painful terminal extension

Radiology


https://doi.org/10.1148/rg.293085163

Modality Imaging features
XR Radiographs are usually diagnostic in moderate-to-severe cases.
Tibial tubercle fragmentation: Irregular or fragmented secondary ossification center
Soft-tissue swelling: May be visible anterior to tibial tubercle
Patellar tendon thickening: Occasionally appreciated
Bony prominence: Chronic cases may develop ossicle or enlarged tubercle
US • Hypoechoic swelling: Apophyseal edema
• Fragmentation: May be visible within tibial tubercle
• Patellar tendon changes: Tendon thickening or inflammation near insertion
MR • T1: Fragmented or irregular tibial tubercle apophysis
• T2/STIR: High signal (edema) in apophysis, adjacent marrow, or patellar tendon
• Chronic phase: Fibrous changes, possible patellar tendinosis, and ossicle formation

![Osgood-Schlatter syndrome in three boys aged 14–16 years with varying degrees of the disease. (a) Radiograph shows a punctate focus of ossification (arrow) at the site of the patellar tendon insertion. (b) Radiograph shows heterotopic bone formation at the tibial tubercle with overlying soft-tissue swelling. (c) Radiograph shows heterotopic bone formation. (d) Corresponding MR image shows edema at the tibial tubercle and in adjacent soft tissues (arrowhead)

Dupuis CS, Westra SJ, Makris J, Wallace EC. Injuries and Conditions of the Extensor Mechanism of the Pediatric Knee. Radiographics. 2009;29(3):877-886. doi:https://doi.org/10.1148/rg.293085163](attachment:ac82627e-46ad-44b2-82da-156f96fed515:image.png)

Osgood-Schlatter syndrome in three boys aged 14–16 years with varying degrees of the disease. (a) Radiograph shows a punctate focus of ossification (arrow) at the site of the patellar tendon insertion. (b) Radiograph shows heterotopic bone formation at the tibial tubercle with overlying soft-tissue swelling. (c) Radiograph shows heterotopic bone formation. (d) Corresponding MR image shows edema at the tibial tubercle and in adjacent soft tissues (arrowhead)

Dupuis CS, Westra SJ, Makris J, Wallace EC. Injuries and Conditions of the Extensor Mechanism of the Pediatric Knee. Radiographics. 2009;29(3):877-886. doi:https://doi.org/10.1148/rg.293085163

![Osgood–Schlatter disease on the ultrasound image. (a) Irregular contour of the ossification center of the tibial tuberosity apophysis. (b) Increased vascularity at the attachment site of the patellar ligament observed on Power Doppler ultrasound.

Maruszczak K, Madej T, Gawda P. Lower Limb Osteochondrosis and Apophysitis in Young Athletes—A Comprehensive Review. Applied Sciences. 2024; 14(24):11795. https://doi.org/10.3390/app142411795](attachment:81b259c4-6d6e-4a98-964b-488861af85eb:image.png)

Osgood–Schlatter disease on the ultrasound image. (a) Irregular contour of the ossification center of the tibial tuberosity apophysis. (b) Increased vascularity at the attachment site of the patellar ligament observed on Power Doppler ultrasound.

Maruszczak K, Madej T, Gawda P. Lower Limb Osteochondrosis and Apophysitis in Young Athletes—A Comprehensive Review. Applied Sciences. 2024; 14(24):11795. https://doi.org/10.3390/app142411795

Differentials