“Target” sign of neurofibroma. (a) Axial T2-weighted image demonstrates a heterogeneously hyperintense extradural mass extending into the left C2–C3 neuroforamen, which shows concentric rings of signal intensity (white solid arrow). (b) This cross-sectional appearance resembles a “target” and is a characteristic, but not pathognomonic finding of neurofibromas. (c) Coronal short tau inversion recovery (STIR) in a child with NF1 demonstrates numerous “target” signs (white open arrows) in a plexiform neurofibroma of the right face.
Koontz NA, Seltman TA, Kralik SF, Mosier KM, Harnsberger HR. Classic signs in head and neck imaging. Clinical Radiology. 2016;71(12):1211-1222. doi:10.1016/j.crad.2016.09.006
(a) Coronal «saturated» T2-weighted and (b) axial post-contrast T1FS-weighted images. Multiple neurofibromas (arrows) in a pediatric patient with NF1. The “target sign” (central area of hypointensity in T2) can be observed (arrowheads).
Marrazzo A, Cacchione A, Rossi S, Carboni A, Gandolfo C, Carai A, Mastronuzzi A, Colafati GS. Intradural Pediatric Spinal Tumors: An Overview from Imaging to Novel Molecular Findings. Diagnostics. 2021; 11(9):1710. https://doi.org/10.3390/diagnostics11091710