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Tufted Angioma (TA) is a rare benign vascular tumor of infancy and childhood, composed of capillary proliferations in the dermis and subcutaneous tissue.

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• Histologically characterized by “cannonball” tufts of capillaries scattered in the dermis.
• It shares a clinical and pathological spectrum with Kaposiform Hemangioendothelioma (KHE).

Epidemiology

• Onset: Infancy or early childhood (occasionally congenital, rarely in adults).
• Very rare.
• Equal sex distribution.

Etiopathology

• Exact cause unclear; likely developmental vascular anomaly.
• Histology:
  • Rounded “cannonball” lobules of capillaries scattered in dermis/subcutis.
  • Lymphatic channels often present.
  • Intermediate features between infantile hemangioma (benign) and KHE (locally aggressive).

Clinical Features

Cutaneous lesion:

• Common sites: neck, upper trunk, proximal extremities.
• Red–brown to violaceous plaque or nodule.
• Ill-defined, indurated, slowly enlarging.
• May be tender or painful.

Kasabach–Merritt Phenomenon (KMP):