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Venous leg ulcers (VLUs) are the most common type of chronic lower limb ulcer, accounting for 60–80% of all leg ulcers. They are a direct complication of Chronic venous insufficiency (CVI) , resulting from sustained venous hypertension, most often due to valvular incompetence, venous obstruction, or both.

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Understanding Leg and Foot Ulcers

Pathophysiology


Cartoon of the pathophysiology of venous leg ulcers (VLUs). a The effects of valve incompetence and b the effects on tissues that lead to lipodermatosclerosis, cell death and ulceration. (Figures a and b were reprinted with permission from Mani R. Chronic Wound Management—the Evidence for Change, Parthenon Press 2002; copyright 2002 by Mani)

Cartoon of the pathophysiology of venous leg ulcers (VLUs). a The effects of valve incompetence and b the effects on tissues that lead to lipodermatosclerosis, cell death and ulceration. (Figures a and b were reprinted with permission from Mani R. Chronic Wound Management—the Evidence for Change, Parthenon Press 2002; copyright 2002 by Mani)

Clinical Features


Feature Details
Pain Usually mild, may increase with infection
Appearance Irregular, shallow ulcers with granulation tissue and exudate
Surrounding skin Hyperpigmentation (hemosiderin), lipodermatosclerosis, varicosities
Edema Pitting edema often present
Discharge Common; may be copious and foul-smelling if infected

![a Typical appearance of patient with lipodermatosclerosis. The skin is flaky and there is a brownish discoloration. The skin can have a waxy feel to it. b A venous ulcer on the medial aspect of the leg

Xie, T., Ye, J., Rerkasem, K. et al. The venous ulcer continues to be a clinical challenge: an update. Burn Trauma 6, 18 (2018). https://doi.org/10.1186/s41038-018-0119-y](attachment:b70cf03f-6d2a-497d-bcbb-ff1465c97e81:41038_2018_119_Fig2_HTML.webp)

a Typical appearance of patient with lipodermatosclerosis. The skin is flaky and there is a brownish discoloration. The skin can have a waxy feel to it. b A venous ulcer on the medial aspect of the leg

Xie, T., Ye, J., Rerkasem, K. et al. The venous ulcer continues to be a clinical challenge: an update. Burn Trauma 6, 18 (2018). https://doi.org/10.1186/s41038-018-0119-y

Complications


Radiology